Description

3-[(2R,3R,4S,5R)-2-(2-Amino-6-Oxo-3H-Purin-9-Yl)-4-Hydroxy-5-(Hydroxymethyl)Oxolan-3-Yl]-1-Methyl-1-Nitroso-Urea is a chemically modified nucleoside analog of significant interest in advanced pharmaceutical research and development. This compound is valued for its role as a key synthetic intermediate and a potential building block for novel therapeutic agents. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of nucleoside-based drugs, including antivirals and anticancer therapies.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel nucleoside analog drugs targeting viral infections and cancer.
• Antiviral Drug Research: Used in the R&D of prodrugs and active pharmaceutical ingredients (APIs) for hepatitis, HIV, and other viral diseases.
• Oncology Research: Investigated as a building block for chemotherapeutic agents designed to interfere with DNA/RNA synthesis in cancer cells.
• Biochemical Tool Compound: Employed in enzymatic studies and as a probe to understand cellular nucleotide metabolism and related pathways.
• Process Chemistry & Scale-up: Serves as a high-purity intermediate for process optimization and pilot-scale manufacturing of advanced therapeutics.
• Academic & Contract Research: Utilized in university laboratories and CROs (Contract Research Organizations) for fundamental medicinal chemistry studies.

Basic Information

Product Name	3-[(2R,3R,4S,5R)-2-(2-Amino-6-Oxo-3H-Purin-9-Yl)-4-Hydroxy-5-(Hydroxymethyl)Oxolan-3-Yl]-1-Methyl-1-Nitroso-Urea
CAS No.	66779-33-7
Molecular Formula	C12H16N8O6
Molecular Weight	344.30 g/mol
Synonyms	1-Methyl-3-[(2R,3R,4S,5R)-2-(2-amino-6-oxo-3H-purin-9-yl)-4-hydroxy-5-(hydroxymethyl)oxolan-3-yl]-1-nitrosourea; 3-(2'-Deoxyadenosin-N6-yl)-1-methyl-1-nitrosourea; 3-(N6-Deoxyadenosinyl)-1-methyl-1-nitrosourea; 1-Methyl-1-nitroso-3-(N6-deoxyadenosinyl)urea; MNNG-deoxyadenosine adduct; Nitrosourea-deoxyadenosine conjugate
EINECS	Contact for details

Quality Control

Our 3-[(2R,3R,4S,5R)-2-(2-Amino-6-Oxo-3H-Purin-9-Yl)-4-Hydroxy-5-(Hydroxymethyl)Oxolan-3-Yl]-1-Methyl-1-Nitroso-Urea is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific research or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.