Description

Ethyl 4-Methoxy-3-Oxo-Butanoate is a versatile keto-ester building block, also known as ethyl 4-methoxyacetoacetate, prized for its reactive β-keto ester functionality. This compound is essential for synthesizing complex heterocyclic and pharmaceutical intermediates, offering a critical pathway for constructing pyrazoles, pyrimidines, and other fine chemicals. It is primarily needed by research and development laboratories, pharmaceutical manufacturers, and agrochemical producers for advanced organic synthesis.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for heterocyclic compounds.
• Agrochemical Synthesis: Building block for creating advanced pesticides, herbicides, and plant growth regulators.
• Fine Chemical Production: Used in the manufacture of dyes, pigments, and specialty performance chemicals.
• Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies.
• Flavor and Fragrance Industry: Serves as an intermediate for certain aroma chemicals and flavoring agents.

Basic Information

Product Name	Ethyl 4-Methoxy-3-Oxo-Butanoate
CAS No.	66762-68-3
Molecular Formula	C7H12O4
Molecular Weight	160.17 g/mol
Synonyms	Ethyl 4-Methoxyacetoacetate; 4-Methoxy-3-oxobutanoic Acid Ethyl Ester; Ethyl 4-Methoxy-3-oxobutyrate; Ethyl (4-Methoxy-3-oxo)butyrate; Acetoacetic Acid Ethyl Ester 4-Methyl Ether; 3-Oxo-4-methoxybutyric Acid Ethyl Ester; Ethyl β-Methoxyacetoacetate
EINECS	Contact for details

Quality Control

Our Ethyl 4-Methoxy-3-Oxo-Butanoate is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chromatography (HPLC/GC) and spectroscopic methods, to ensure high purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee reliable performance in your synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (20°C)	1.420 - 1.430
Density (20°C)	1.090 - 1.110 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.