Description

Methyl 2-Isocyanobenzoate is a versatile and reactive organic intermediate, specifically an isocyanate ester of benzoic acid. This compound is valued for its role as a key building block in the synthesis of more complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily utilized by R&D chemists and process development scientists in the fine chemical and active pharmaceutical ingredient (API) manufacturing sectors.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various heterocyclic compounds and active pharmaceutical ingredients (APIs), including potential kinase inhibitors and other biologically active molecules.
• Agrochemical Synthesis: Used in the research and development of novel pesticides, herbicides, and fungicides, where the isocyanate group enables the formation of ureas and other functional groups.
• Polymer Chemistry: Serves as a monomer or cross-linking agent in the development of specialized polyurethanes and other polymers with tailored properties.
• Chemical Research: Employed in academic and industrial laboratories for the construction of complex organic frameworks, including dyes, pigments, and materials science applications.
• Peptide Mimetics: Useful in medicinal chemistry for creating peptide analogs and isosteres to modulate biological activity and stability.

Basic Information

Product Name	Methyl 2-Isocyanobenzoate
CAS No.	66715-31-9
Molecular Formula	C9H7NO3
Molecular Weight	177.16 g/mol
Synonyms	2-Isocyanobenzoic Acid Methyl Ester; Methyl 2-Isocyanatobenzoate; Methyl o-Isocyanatobenzoate; Benzoic Acid, 2-Isocyanato-, Methyl Ester; Methyl Anthranilate N-Carboxy Anhydride (Methyl Isatoic Anhydride analog)
EINECS	Contact for details

Quality Control

Our Methyl 2-Isocyanobenzoate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding synthetic applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality system is designed to meet the stringent requirements of the pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from heat, sparks, open flames, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.