Description

Ethyl 4-(tert-Butoxycarbonyl)-3-oxopentanoate is a high-purity, protected β-ketoester derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its dual functionality, offering both a reactive ketone and a protected carboxylic acid group, which enables precise and efficient multi-step chemical transformations. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for the synthesis of complex molecules, active pharmaceutical ingredients (APIs), and specialized intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs), especially those requiring β-ketoester chemistry.
• Peptide Mimetics & Conjugate Synthesis: Used in the preparation of peptide analogs and bioconjugates, leveraging the tert-butoxycarbonyl (Boc) protecting group for selective deprotection.
• Fine Chemical Synthesis: Serves as a versatile building block for constructing heterocyclic compounds, natural product analogs, and other high-value specialty chemicals.
• Agrochemical Research: Employed in the development and scale-up of novel agrochemicals and plant protection agents.
• Material Science Precursor: Potential use in the synthesis of monomers or ligands for advanced polymeric materials and metal-organic frameworks (MOFs).

Basic Information

Product Name	Ethyl 4-(tert-Butoxycarbonyl)-3-oxopentanoate
CAS No.	66643-80-9
Molecular Formula	C₁₂H₂₀O₅
Molecular Weight	244.28 g/mol
Synonyms	Ethyl 4-(Boc)-3-oxopentanoate; 4-(tert-Butoxycarbonyl)-3-oxopentanoic Acid Ethyl Ester; Ethyl 3-Oxo-4-[(2-methyl-2-propanyl)oxycarbonyl]pentanoate; 3-Oxo-4-[(tert-butoxy)carbonyl]pentanoic Acid Ethyl Ester; Boc-β-ketoester; Ethyl 4-Boc-acetoacetate; Pentanoic acid, 4-[(1,1-dimethylethoxy)carbonyl]-3-oxo-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 4-(tert-Butoxycarbonyl)-3-oxopentanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.