Description

6-Chloronicotinoyl Chloride 97 is a high-purity, reactive chemical intermediate essential for advanced organic synthesis. Its value lies in its dual functional groups, which enable efficient construction of complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is critically needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce the 6-chloronicotinate pharmacophore into target structures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, including kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides that incorporate nicotinic acid derivatives.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands used in catalytic systems and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of functional polymers and advanced organic materials with specific electronic or binding properties.
• Custom Synthesis and Contract Manufacturing: A vital reagent for fine chemical and CDMO (Contract Development and Manufacturing Organization) facilities producing bespoke compounds for clients.

Basic Information

Product Name	6-Chloronicotinoyl Chloride 97
CAS No.	66608-11-5
Molecular Formula	C6H3Cl2NO
Molecular Weight	176.00 g/mol
Synonyms	6-Chloropyridine-3-carbonyl chloride; 6-Chloronicotinic acid chloride; 3-Chloro-6-pyridinecarbonyl chloride; 6-Chloro-3-pyridinecarbonyl chloride; Nicotinoyl chloride, 6-chloro-; 6-Chloronicotinyl chloride; 66608-11-5; 6-Chloro-3-pyridinylcarbonyl chloride
EINECS	Contact for details

Quality Control

Our 6-Chloronicotinoyl Chloride 97 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity verification and identity confirmation by FT-IR and NMR spectroscopy, to ensure it meets the high standards required for sensitive synthesis applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.