Description

2-Bromopyridine-4-Carboxylic Acid is a versatile brominated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its value lies in the reactive bromine atom and carboxylic acid functional group, which allow for selective cross-coupling reactions and further derivatization. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a starting material for creating novel pyridine-based ligands for metal catalysis and coordination chemistry.
• Material Science Research: Building block for synthesizing functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for biochemical research.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for use in multi-step custom synthesis projects for clients.

Basic Information

Product Name	2-Bromopyridine-4-Carboxylic Acid
CAS No.	66572-56-3
Molecular Formula	C6H4BrNO2
Molecular Weight	202.01 g/mol
Synonyms	4-Carboxy-2-bromopyridine; 2-Bromoisonicotinic Acid; 2-Bromo-4-pyridinecarboxylic Acid; 2-Bromopyridine-4-carboxylic acid; 2-Bromo-4-carboxypyridine; Isonicotinic acid, 2-bromo-; 2-Bromopyridine-4-carboxylate
EINECS	Contact for details

Quality Control

Our 2-Bromopyridine-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.