Description

1,4-Dioxaspiro[4.4]Nonane-6-Carboxaldehyde is a versatile spirocyclic aldehyde building block of significant interest in advanced organic synthesis. Its unique fused ring system containing both acetal and aldehyde functionalities makes it a valuable precursor for constructing complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the preparation of advanced pesticide and herbicide molecules, leveraging its spirocyclic structure for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of monomers for specialty polymers with unique thermal or mechanical properties.
• Flavor and Fragrance Chemistry: Acts as a building block for synthesizing complex odorants and flavor compounds with spirocyclic motifs.
• Academic and R&D Laboratories: A valuable reagent for methodological studies in organic chemistry, including novel cyclization and functionalization reactions.

Basic Information

Product Name	1,4-Dioxaspiro[4.4]Nonane-6-Carboxaldehyde
CAS No.	66522-88-1
Molecular Formula	C9H14O3
Molecular Weight	170.21 g/mol
Synonyms	6-Formyl-1,4-dioxaspiro[4.4]nonane; 1,4-Dioxaspiro[4.4]nonane-6-carbaldehyde; Spiro[1,3-dioxolane-2,1'-cyclopentane]-4-carboxaldehyde; 6-Carboxaldehyde-1,4-dioxaspiro[4.4]nonane; Cyclopentanone ethylene ketal-2-carboxaldehyde; 2-(2-Oxopropyl)-1,3-dioxolane (tautomeric form); Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our 1,4-Dioxaspiro[4.4]Nonane-6-Carboxaldehyde is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatography (HPLC, GC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.