Description

2-Desoxy-2-(3-Methyl-3-Nitrosoureido)-D-Glucopyranose CAS NO 66395-18-4 is a specialized carbohydrate derivative, a key intermediate in the synthesis of complex bioactive molecules. Its value lies in its unique nitrosoureido functional group, which serves as a versatile precursor for targeted chemical modifications in advanced research and development. This compound is essential for pharmaceutical chemists and biochemists working on novel drug candidates, particularly in oncology and metabolic disease research, where precise molecular scaffolds are critical.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel chemotherapeutic agents and targeted cancer therapies.
• Biochemical Research: Used in the study of carbohydrate-protein interactions and enzyme inhibition mechanisms.
• Glycoconjugate Synthesis: Serves as a precursor for creating complex glycoconjugates with potential diagnostic or therapeutic applications.
• Antibiotic Development: A key starting material in the research and development of next-generation aminoglycoside and nucleoside analog antibiotics.
• Academic & Institutional R&D: Employed in university and government laboratories for fundamental research in medicinal chemistry and chemical biology.
• Process Development: Used by process chemists to scale up and optimize synthetic routes for active pharmaceutical ingredients (APIs).

Basic Information

Product Name	2-Desoxy-2-(3-Methyl-3-Nitrosoureido)-D-Glucopyranose
CAS No.	66395-18-4
Molecular Formula	C8H15N3O7
Molecular Weight	265.22 g/mol
Synonyms	1,5-Anhydro-2-deoxy-2-[(3-methyl-3-nitrosoureido)]-D-glucitol; 2-Deoxy-2-[(3-methyl-3-nitrosoureido)]-D-glucopyranose; Streptozocin Impurity; STZ Impurity; Nitrosourea-Glucose Conjugate; U-9889; Antibiotic U-9889; NSC 85998
EINECS	Contact for details

Quality Control

Every batch of 2-Desoxy-2-(3-Methyl-3-Nitrosoureido)-D-Glucopyranose is produced and tested under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and consistency for your critical research and development projects. A detailed Certificate of Analysis (COA) is supplied with each shipment, documenting key parameters such as assay, related substances, and residual solvents. Our quality commitment supports compliance with cGMP and ISO guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant use and storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.