Description

(3R,5'Ar)-5-(3-Furyl)-7'β-Methyl-3',5',5'Aα,7',8',8'Aα-Hexahydrospiro[Furan-3(2H),6'-[6H]Naphtho[1,8-Bc]Furan]-2,2'(4'H)-Dione is a complex, high-purity spirocyclic furanone derivative of significant interest in advanced organic synthesis. This compound serves as a sophisticated chiral building block and key intermediate for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily utilized by research institutions and industrial R&D departments focused on pharmaceuticals, agrochemicals, and material science, where its unique fused ring structure enables the construction of molecules with specific stereochemistry and biological activity.

Application

• Pharmaceutical Intermediate: A critical chiral precursor in the multi-step synthesis of potential drug candidates, particularly for central nervous system (CNS) or anti-inflammatory targets.
• Agrochemical Research: Used in the development of new-generation herbicides or pesticides, leveraging its complex heterocyclic framework.
• Organic Synthesis Building Block: Employed in academic and industrial laboratories for constructing complex natural product analogs and novel molecular architectures.
• Material Science Precursor: Investigated for the synthesis of specialized organic ligands or monomers for advanced polymeric materials.
• Asymmetric Catalysis Studies: Serves as a substrate or a template in the development and testing of new chiral catalysts and synthetic methodologies.

Basic Information

Product Name	(3R,5'Ar)-5-(3-Furyl)-7'β-Methyl-3',5',5'Aα,7',8',8'Aα-Hexahydrospiro[Furan-3(2H),6'-[6H]Naphtho[1,8-Bc]Furan]-2,2'(4'H)-Dione
CAS No.	66275-07-8
Molecular Formula	C19H18O5
Molecular Weight	326.34 g/mol
Synonyms	7'β-Methyl-5-(3-furyl)-3',5',5'Aα,7',8',8'Aα-hexahydrospiro[furan-3(2H),6'-[6H]naphtho[1,8-bc]furan]-2,2'(4'H)-dione; (3R,5'ar)-5-(3-Furanyl)-7'β-methyl-3',5',5'aα,7',8',8'aα-hexahydrospiro[furan-3(2H),6'-[6H]naphtho[1,8-bc]furan]-2,2'(4'H)-dione; Hexahydrospiro[furan-3(2H),6'-[6H]naphtho[1,8-bc]furan]-2,2'(4'H)-dione derivative; Spiro[naphtho[1,8-bc]furan-6(6H),3'-furan]-2,2'(4'H)-dione derivative; CAS 66275-07-8
EINECS	Contact for details

Quality Control

Our (3R,5'Ar)-5-(3-Furyl)-7'β-Methyl-3',5',5'Aα,7',8',8'Aα-Hexahydrospiro[Furan-3(2H),6'-[6H]Naphtho[1,8-Bc]Furan]-2,2'(4'H)-Dione is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity analysis, to ensure identity, potency, and consistency. A detailed Certificate of Analysis (COA) is provided, confirming compliance with customer specifications and relevant industry standards for research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.