Description

Hexadecyl 2-[4-[Bis(2-Chloroethyl)Amino]Phenyl]Acetate is a synthetic organic compound belonging to the class of nitrogen mustard derivatives. This specialized chemical is valued for its role as a key intermediate in advanced pharmaceutical research and development, particularly in the synthesis of targeted therapeutic agents. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of novel oncology and cytostatic treatments.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of nitrogen mustard-based chemotherapeutic agents and prodrugs.
• Oncology Research: Used in academic and industrial R&D for studying alkylating agent mechanisms and developing new anti-cancer compounds.
• Bioconjugation Studies: Serves as a functionalized linker or payload in antibody-drug conjugate (ADC) research due to its reactive chloroethyl groups.
• Biochemical Tool Compound: Employed in laboratory settings to investigate DNA alkylation and cellular apoptosis pathways.
• Preclinical Development: Utilized in the formulation and testing stages of new drug candidates prior to clinical trials.

Basic Information

Product Name	Hexadecyl 2-[4-[Bis(2-Chloroethyl)Amino]Phenyl]Acetate
CAS No.	66232-29-9
Molecular Formula	C30H53Cl2NO2
Molecular Weight	530.65 g/mol
Synonyms	1-Hexadecyl 2-(4-[bis(2-chloroethyl)amino]phenyl)acetate; Cetyl 2-[4-[Bis(2-chloroethyl)amino]phenyl]acetate; N,N-Bis(2-chloroethyl)-4-(2-hexadecyloxy-2-oxoethyl)aniline; 4-[Bis(2-chloroethyl)amino]benzeneacetic acid hexadecyl ester; Mustard cetyl ester derivative; Chlorambucil cetyl ester; Aniline mustard derivative ester
EINECS	Contact for details

Quality Control

Our Hexadecyl 2-[4-[Bis(2-Chloroethyl)Amino]Phenyl]Acetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR and IR for structural confirmation, and specific tests for residual solvents and related substances. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.