Description

Butanedioic Acid, 2-Hydroxy-, 1-(Phenylmethyl) Ester, (2S)- is a high-purity chiral intermediate of significant importance in advanced organic synthesis. This compound matters for its role as a key building block in the production of enantiomerically pure pharmaceuticals and fine chemicals. Industries that require precise stereochemistry, such as pharmaceutical R&D, agrochemical manufacturing, and specialty chemical synthesis, are the primary users of this material.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of active pharmaceutical ingredients (APIs) requiring specific (S)-configuration.
• Asymmetric Catalyst Ligand Precursor: Used in the development and manufacture of ligands for metal-catalyzed asymmetric reactions.
• Fine Chemical Synthesis: Serves as a starting material or intermediate for complex molecules in agrochemicals, flavors, and fragrances.
• Biochemical Research: Employed in academic and industrial research for studying enzyme mechanisms and chiral recognition processes.
• Polymer Modification: Potential use as a monomer or co-monomer for introducing specific functional groups into polymer chains.

Basic Information

Product Name	Butanedioic Acid, 2-Hydroxy-, 1-(Phenylmethyl) Ester, (2S)-
CAS No.	66178-04-9
Molecular Formula	C11H12O5
Molecular Weight	224.21 g/mol
Synonyms	(S)-(-)-2-Hydroxysuccinic acid 1-benzyl ester; (S)-(-)-Malic acid 1-benzyl ester; (2S)-1-Benzyl 2-hydroxybutanedioate; (S)-1-Benzyl hydrogen malate; L-(-)-Malic acid benzyl ester; Benzyl (S)-(-)-hydrogen malate; 1-Benzyl (2S)-2-hydroxybutanedioate; Benzyl L-malate
EINECS	Contact for details

Quality Control

Our Butanedioic Acid, 2-Hydroxy-, 1-(Phenylmethyl) Ester, (2S)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat sources and incompatible materials. Due to its light-sensitive nature, the container should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.