Description

1-(4-Fluorobenzyl)-1,2-Dihydro-2-Oxopyridine-3-Carboxylic Acid is a high-purity, synthetically versatile organic compound that serves as a critical building block in advanced chemical synthesis. Its value lies in its unique molecular structure, which incorporates both a fluorinated benzyl group and a dihydropyridone carboxylic acid moiety, enabling precise modifications for targeted applications. This intermediate is essential for research and development chemists and manufacturers in the pharmaceutical and agrochemical sectors seeking to develop novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in therapeutic areas requiring fluorinated compounds for enhanced metabolic stability and bioavailability.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the fluorine atom can improve biological activity and environmental persistence profiles.
• Chemical Synthesis Building Block: Employed in organic synthesis for constructing complex heterocyclic frameworks due to its reactive carboxylic acid and ketone functional groups.
• Material Science Research: Investigated as a monomer or functional additive for creating specialized polymers with specific optical or electronic properties.
• Bioconjugation & Probe Development: Utilized in the design of fluorescent probes or biochemical tools where the fluorobenzyl group aids in targeting or detection.

Basic Information

Product Name	1-(4-Fluorobenzyl)-1,2-Dihydro-2-Oxopyridine-3-Carboxylic Acid
CAS No.	66158-41-6
Molecular Formula	C13H10FNO3
Molecular Weight	247.22 g/mol
Synonyms	3-Pyridinecarboxylic acid, 1,2-dihydro-1-[(4-fluorophenyl)methyl]-2-oxo-; 1-(4-Fluorobenzyl)-2-oxo-1,2-dihydropyridine-3-carboxylic acid; 1,2-Dihydro-1-[(4-fluorophenyl)methyl]-2-oxo-3-pyridinecarboxylic acid; 1-(4-Fluorobenzyl)-1,2-dihydro-2-oxonicotinic acid; 2-Oxo-1-(4-fluorobenzyl)-1,2-dihydropyridine-3-carboxylic acid; 3-Carboxy-1-(4-fluorobenzyl)-2(1H)-pyridinone; 1-(p-Fluorobenzyl)-1,2-dihydro-2-oxopyridine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 1-(4-Fluorobenzyl)-1,2-Dihydro-2-Oxopyridine-3-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. The material is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment. We support compliance with relevant regulatory frameworks for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.