Description

4-Chloro-2-(Methylsulfonyl)Pyridine is a high-purity, versatile heterocyclic building block characterized by its reactive chloro and methylsulfonyl substituents. This compound matters as a critical intermediate for synthesizing advanced molecules in pharmaceutical and agrochemical research, enabling the introduction of key functional groups. It is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, leveraging its reactive sites for structural diversification.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Building block for synthesizing functionalized pyridine derivatives used in electronic materials and organic semiconductors.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke chemical production and scale-up projects.
• Academic and Industrial R&D: Utilized in discovery chemistry for library synthesis and structure-activity relationship (SAR) studies.

Basic Information

Item	Details
Product Name	4-Chloro-2-(Methylsulfonyl)Pyridine
CAS No.	66154-70-9
Molecular Formula	C6H6ClNO2S
Molecular Weight	191.63 g/mol
Synonyms	4-Chloro-2-methanesulfonylpyridine; 2-Methylsulfonyl-4-chloropyridine; 4-Chloro-2-(methylsulfonyl)pyridine; 4-Chloro-2-pyridyl methyl sulfone; 66154-70-9; 4-Chloro-2-mesylpyridine
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-(Methylsulfonyl)Pyridine is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.