Description

6-(Methylsulfonyl)Nicotinonitrile is a high-purity, versatile heterocyclic building block featuring a pyridine core substituted with a nitrile and a methylsulfonyl group. This compound is valued for its role as a key synthetic intermediate in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of potential drug candidates, particularly kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its bioactive scaffold.
• Material Science: Serves as a building block for creating specialized ligands, polymers, and functional organic materials.
• Chemical Synthesis: Employed in cross-coupling reactions and as a substrate for further functionalization of the pyridine ring system.
• Academic & Contract Research: Utilized in universities and CROs for methodological studies and the exploration of new chemical spaces.

Basic Information

Product Name	6-(Methylsulfonyl)Nicotinonitrile
CAS No.	66154-68-5
Molecular Formula	C7H6N2O2S
Molecular Weight	182.20 g/mol
Synonyms	6-(Methylsulfonyl)pyridine-3-carbonitrile; 3-Cyano-6-(methylsulfonyl)pyridine; Nicotinonitrile, 6-(methylsulfonyl)-; 6-Methanesulfonylnicotinonitrile; 6-Methylsulfonyl-3-pyridinecarbonitrile; 3-Pyridinecarbonitrile, 6-(methylsulfonyl)-; 66154-68-5
EINECS	Contact for details

Quality Control

Our 6-(Methylsulfonyl)Nicotinonitrile is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.