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2-Acetylamino-5-Iodopyridine CAS NO 66131-78-0
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CAS No.:66131-78-0
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
2-Acetylamino-5-Iodopyridine is a halogenated pyridine derivative that serves as a versatile and high-value synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring both an acetyl-protected amino group and an iodine atom, makes it a critical building block for constructing complex heterocyclic systems. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and fine chemicals.
Application
- Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other targeted therapies.
- Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that require halogenated heterocyclic cores.
- Material Science: Building block for creating specialized ligands, catalysts, and organic electronic materials.
- Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Buchwald-Hartwig couplings.
- Chemical Biology: Used in the synthesis of molecular probes and labeled compounds for biochemical research.
- Custom Synthesis: Serves as a starting material for contract research organizations (CROs) and fine chemical manufacturers producing bespoke compounds.
Basic Information
| Product Name | 2-Acetylamino-5-Iodopyridine |
| CAS No. | 66131-78-0 |
| Molecular Formula | C7H7IN2O |
| Molecular Weight | 262.05 g/mol |
| Synonyms | N-(5-Iodopyridin-2-yl)acetamide; 5-Iodo-2-acetamidopyridine; 2-Acetamido-5-iodopyridine; Acetamide, N-(5-iodo-2-pyridinyl)-; 5-Iodo-2-pyridinylacetamide; 2-Pyridinamine, 5-iodo-N-acetyl-; 2-Acetylamino-5-iodo-pyridine |
| EINECS | Contact for details |
Quality Control
Our 2-Acetylamino-5-Iodopyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, prolonged exposure to light should be avoided.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 97.0% |
| Melting Point | Contact for details |
| Loss on Drying | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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