Description

1-Benzyl-Piperidine-2-Carboxylic Acid Hydrochloride is a high-purity, pharmaceutically relevant organic salt, widely recognized by its CAS number 66120-28-3. This compound serves as a critical building block (synthon) and intermediate in the synthesis of complex molecules, offering a versatile piperidine scaffold for medicinal chemistry. It is primarily utilized by pharmaceutical R&D and fine chemical manufacturers for developing new active pharmaceutical ingredients (APIs) and other specialty chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting the central nervous system (CNS).
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries and exploring structure-activity relationships (SAR).
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a precursor in multi-step synthetic routes for producing complex therapeutic molecules.
• Chemical Biology Probes: Employed in the development of research tools and probes to study biological pathways and enzyme functions.
• Fine Chemical Production: Utilized in the manufacture of specialty chemicals, catalysts, and advanced materials requiring a functionalized piperidine moiety.
• Academic & Industrial R&D: A valuable reagent for synthetic organic chemistry research in both university and corporate laboratory settings.

Basic Information

Product Name	1-Benzyl-Piperidine-2-Carboxylic Acid Hydrochloride
CAS No.	66120-28-3
Molecular Formula	C14H19NO2 • HCl
Molecular Weight	269.77 g/mol (Free base: 233.31 g/mol)
Synonyms	1-Benzyl-2-piperidinecarboxylic acid hydrochloride; 1-Benzylpipecolinic acid hydrochloride; (1-Benzylpiperidin-2-yl)carboxylic acid hydrochloride; 2-Piperidinecarboxylic acid, 1-benzyl-, hydrochloride; NSC 403697; 1-Bzl-Pip-OH • HCl; 1-Benzyl-DL-pipecolic acid hydrochloride
EINECS	Contact for details

Quality Control

Our 1-Benzyl-Piperidine-2-Carboxylic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistent quality suitable for research and pharmaceutical applications. Comprehensive Certificates of Analysis (COA) are provided, detailing identity, purity, and impurity profiles as determined by HPLC, NMR, and other relevant methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.