Description

n-Acetylmuramyl-Aminobutyryl-Isoglutamine is a synthetic muramyl dipeptide (MDP) derivative, a key structural component of bacterial peptidoglycan. This compound is of significant interest for its role as a potent immunomodulator and adjuvant, capable of stimulating both innate and adaptive immune responses. It is primarily utilized by research institutions and pharmaceutical developers focused on vaccine formulation, immunotherapy, and immunological research.

Application

• Immunological Research: Used as a reference standard and active component in studies of innate immunity, NOD2 receptor signaling, and inflammatory pathways.
• Vaccine Adjuvant Development: Investigated for enhancing the efficacy and longevity of immune responses in next-generation prophylactic and therapeutic vaccines.
• Pharmaceutical Intermediates: Serves as a critical building block in the synthesis of more complex immunostimulatory compounds and drug candidates.
• Cell Culture & In Vitro Studies: Applied in macrophage activation studies and other cell-based assays to model immune system interactions.

Basic Information

Product Name	n-Acetylmuramyl-Aminobutyryl-Isoglutamine
CAS No.	66112-58-1
Molecular Formula	C22H38N4O11
Molecular Weight	534.56 g/mol
Synonyms	MDP-Abu; N-Acetylmuramyl-L-alanyl-D-isoglutaminyl-L-2-aminobutyramide; Muramyl Dipeptide Aminobutyryl Derivative; L-Ala-γ-D-Glu-mDAP; Adjuvant Peptide; Immunostimulant MDP analog; N-Acetylmuramyl-L-alanyl-D-isoglutaminyl-L-α-aminobutyrylamide
EINECS	Contact for details

Quality Control

Our n-Acetylmuramyl-Aminobutyryl-Isoglutamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent controls for residual solvents and impurities. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.