Description

6-Chloro-1,5-Naphthyridine-4-Oxo-3-Carboxylic Acid Ethyl Ester is a high-purity, advanced pharmaceutical intermediate with a distinct heterocyclic structure. This compound matters as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting infectious diseases and oncology. It is primarily needed by R&D chemists and process development teams in the pharmaceutical and fine chemical industries for creating novel drug candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel antibacterial and antiviral agents, particularly quinolone and naphthyridine-based drugs.
• Organic Synthesis Building Block: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new chemical entities.
• Research & Development: Essential for academic and industrial research focused on heterocyclic chemistry and drug discovery programs.
• Process Chemistry: Serves as a starting material for scaling up the production of target molecules under Good Manufacturing Practice (GMP) conditions.
• Agrochemical Intermediates: Potential use in the development of new crop protection agents with specific biological activity.

Basic Information

Product Name	6-Chloro-1,5-Naphthyridine-4-Oxo-3-Carboxylic Acid Ethyl Ester
CAS No.	66093-16-1
Molecular Formula	C11H9ClN2O3
Molecular Weight	252.66 g/mol
Synonyms	Ethyl 6-Chloro-4-oxo-1,5-naphthyridine-3-carboxylate; 6-Chloro-4-oxo-1,5-naphthyridine-3-carboxylic Acid Ethyl Ester; 1,5-Naphthyridine-3-carboxylic acid, 6-chloro-4-oxo-, ethyl ester; 66093-16-1; Ethyl 6-chloro-4-oxo-1,5-naphthyridine-3-carboxylate; 6-Chloro-4-oxo-1,5-naphthyridin-3-yl ethyl carboxylate
EINECS	Contact for details

Quality Control

Our 6-Chloro-1,5-Naphthyridine-4-Oxo-3-Carboxylic Acid Ethyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for pharmaceutical R&D. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality management system supports compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.