Description

2-Bromo-5-Methyl-4-Nitropyridine is a versatile and high-value halogenated nitropyridine derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both bromine and nitro substituents, makes it an essential building block for constructing complex molecular architectures. This compound is particularly valuable for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop active ingredients and novel chemical entities. The product is supplied under stringent quality control to ensure reliability and consistency for demanding synthesis workflows.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing pyridine cores.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as components for OLEDs or conductive polymers.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl systems.
• Nucleophilic Aromatic Substitution: The nitro group activates the pyridine ring for substitution reactions, enabling further functionalization.

Basic Information

Product Name	2-Bromo-5-Methyl-4-Nitropyridine
CAS No.	66092-62-4
Molecular Formula	C6H5BrN2O2
Molecular Weight	217.02 g/mol
Synonyms	4-Nitro-2-bromo-5-methylpyridine; 5-Methyl-2-bromo-4-nitropyridine; 2-Bromo-4-nitro-5-picoline; 2-Bromo-5-methyl-4-nitropyridine; 66092-62-4; Pyridine, 2-bromo-5-methyl-4-nitro-; 4-Nitro-2-bromo-5-methylpyridine
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-5-Methyl-4-Nitropyridine is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing, including HPLC, NMR, and GC-MS analysis, to ensure compliance with industry standards and customer specifications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request and provided with each shipment to guarantee traceability and product integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.