Description

Di-tert-Butyl Acetylenedicarboxylate is a high-purity, specialty diester of acetylenedicarboxylic acid, serving as a versatile and valuable building block in advanced organic synthesis. Its primary value lies in its role as a protected acetylene dicarboxylate equivalent, enabling controlled reactions in complex molecule construction. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for creating novel molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex heterocycles, bioactive molecules, and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators requiring specific acetylene-based motifs.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of polymers with unique electronic or optical properties.
• Organic Synthesis Reagent: Employed in Diels-Alder reactions, [2+2] cycloadditions, and other cyclization strategies to form complex carbon skeletons.
• Ligand and Catalyst Development: Used as a precursor for synthesizing specialized ligands for transition metal catalysis.
• Academic and R&D Laboratories: A critical reagent for methodological development and exploring new synthetic pathways in chemical research.

Basic Information

Product Name	Di-tert-Butyl Acetylenedicarboxylate
CAS No.	66086-33-7
Molecular Formula	C₁₄H₂₀O₄
Molecular Weight	252.31 g/mol
Synonyms	Acetylenedicarboxylic Acid Di-tert-butyl Ester; Di-tert-butyl But-2-ynedioate; Di-t-butyl Acetylenedicarboxylate; DTAD; tert-Butyl Propiolate Dimer; 2-Butynedioic Acid, 1,4-Di-tert-butyl Ester; Bis(1,1-dimethylethyl) 2-Butynedioate
EINECS	Contact for details

Quality Control

Our Di-tert-Butyl Acetylenedicarboxylate is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.