Description

Pyridine, 2-Methoxy-4-[(Trimethylsilyl)Oxy]- (9Ci) is a specialized organosilicon derivative of a methoxypyridine, characterized by its trimethylsilyl-protected phenolic hydroxyl group. This compound serves as a valuable protected intermediate and building block in advanced organic synthesis, particularly where selective deprotection strategies are required. It is primarily utilized by pharmaceutical R&D and fine chemical manufacturers for the development of complex active molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, especially those containing functionalized pyridine cores.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides requiring specific silicon-containing motifs.
• Material Science Precursor: Serves as a monomer or functionalization agent in the development of specialty polymers and advanced organic materials.
• Organic Synthesis Reagent: Employed as a protected synthon in multi-step synthetic routes, facilitating reactions that are sensitive to free phenolic groups.
• Ligand and Catalyst Development: Utilized in the preparation of novel ligands for metal catalysis and organocatalysis research.

Basic Information

Product Name	Pyridine, 2-Methoxy-4-[(Trimethylsilyl)Oxy]- (9Ci)
CAS No.	66080-46-4
Molecular Formula	C9H15NO2Si
Molecular Weight	197.31 g/mol
Synonyms	2-Methoxy-4-(trimethylsilyloxy)pyridine; 4-(Trimethylsilyloxy)-2-methoxypyridine; 2-Methoxypyridin-4-yl trimethylsilyl ether; 4-Trimethylsilyloxy-2-methoxypyridine; 2-Methoxy-4-(trimethylsiloxy)pyridine; 4-(Trimethylsiloxy)-2-methoxypyridine; Pyridine, 2-methoxy-4-[(trimethylsilyl)oxy]-
EINECS	Contact for details

Quality Control

Our Pyridine, 2-Methoxy-4-[(Trimethylsilyl)Oxy]- (9Ci) is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC and NMR, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support compliance with REACH and other global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.