Description

1-Thia-4-Azaspiro[4.5]Decane-3-Carboxylic Acid Hydrochloride is a high-purity, heterocyclic building block of significant interest in advanced organic synthesis. Its unique spirocyclic structure, incorporating both sulfur and nitrogen, makes it a valuable intermediate for constructing complex molecular architectures. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the discovery and development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting the central nervous system (CNS) and other therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic scaffold for bioactivity.
• Chemical Biology & Proteomics: Serves as a specialized scaffold or linker in the design of chemical probes and tools for studying biological systems.
• Material Science Research: Investigated as a monomer or precursor for the synthesis of specialized polymers with unique properties.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and exploration of new chemical space.
• Custom Synthesis & Scale-Up: Supplied for process development and cGMP manufacturing of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	1-Thia-4-Azaspiro[4.5]Decane-3-Carboxylic Acid Hydrochloride
CAS No.	66065-60-9
Molecular Formula	C9H15NO2S • HCl
Molecular Weight	237.75 g/mol
Synonyms	Thiaspirodecanecarboxylic acid hydrochloride; 3-Carboxy-1-thia-4-azaspiro[4.5]decane hydrochloride; 1-Thia-4-azaspiro[4.5]decane-3-carboxylic acid, hydrochloride; Spiro[thiazolidine-4,1'-cyclohexane]-3-carboxylic acid hydrochloride; 66065-60-9; 1-Thia-4-azaspiro[4.5]decane-3-carboxylic acid HCl
EINECS	Contact for details

Quality Control

Our 1-Thia-4-Azaspiro[4.5]Decane-3-Carboxylic Acid Hydrochloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements of research and development applications. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability, consistency, and reliability for your critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.