Description

(6S,7S,12Ar)-5,6,7,8-Tetrahydro-2,3,10,11,12-Pentamethoxy-6,7-Dimethyldibenzo[A,C]Cyclooctene-1,7-Diol CAS NO 66056-20-0 is a complex, high-purity dibenzocyclooctene lignan derivative. This compound is of significant interest for its role as a key intermediate in advanced pharmaceutical synthesis and research into bioactive natural products. It is primarily sought by research institutions and pharmaceutical developers working on novel therapeutic agents, particularly in areas requiring structurally specific chiral molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block for the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard or probe in studies investigating enzyme inhibition, receptor binding, and other biological mechanisms.
• Natural Product Synthesis: A key precursor in the semi-synthesis or total synthesis of bioactive lignans and related natural compounds.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of target molecules in medicinal chemistry.
• Analytical Standard: Provides a high-purity standard for method development and quality control in analytical laboratories (HPLC, LC-MS).

Basic Information

Product Name	(6S,7S,12Ar)-5,6,7,8-Tetrahydro-2,3,10,11,12-Pentamethoxy-6,7-Dimethyldibenzo[A,C]Cyclooctene-1,7-Diol
CAS No.	66056-20-0
Molecular Formula	C24H30O7
Molecular Weight	430.49 g/mol
Synonyms	(-)-Galbelgin; Galbelgin; (6S,7S,12aR)-5,6,7,8-Tetrahydro-2,3,10,11,12-pentamethoxy-6,7-dimethyldibenzo[a,c]cyclooctene-1,7-diol; 1,7-Dihydroxy-2,3,10,11,12-pentamethoxy-6,7-dimethyl-5,6,7,8-tetrahydrodibenzo[a,c]cyclooctene; Lignan F 1896; A natural dibenzocyclooctadiene lignan
EINECS	Contact for details

Quality Control

Our (6S,7S,12Ar)-5,6,7,8-Tetrahydro-2,3,10,11,12-Pentamethoxy-6,7-Dimethyldibenzo[A,C]Cyclooctene-1,7-Diol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling by HPLC, to ensure it meets the exacting standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing identity, purity, and specific test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and in original packaging until use to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.