Description

Spiro[2.3]Hexane-5-Carboxylic Acid, Hydrazide (9Ci) is a specialized spirocyclic organic building block featuring a carboxylic acid hydrazide functional group. This compound is valued for its unique three-dimensional structure and reactive handle, which are critical for constructing complex molecular architectures in advanced research and development. It is primarily sought by pharmaceutical, agrochemical, and advanced materials chemists for applications in medicinal chemistry, ligand synthesis, and the development of novel polymers.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for creating spirocyclic scaffolds with potential biological activity.
• Agrochemical Synthesis: Used in the design and synthesis of new generation herbicides, fungicides, and plant growth regulators that leverage its constrained geometry.
• Ligand and Catalyst Development: Serves as a precursor for chelating ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer & Material Science: Incorporated as a monomer or cross-linking agent to impart rigidity and unique thermal properties to specialty polymers and high-performance materials.
• Chemical Biology & Proteomics: Utilized as a reactive handle for bioconjugation and the synthesis of chemical probes for studying biological systems.
• Academic & Industrial R&D: A valuable reagent for methodological development and exploring new chemical space in synthetic organic chemistry laboratories.

Basic Information

Item	Detail
Product Name	Spiro[2.3]Hexane-5-Carboxylic Acid, Hydrazide (9Ci)
CAS No.	66036-89-3
Molecular Formula	C7H10N2O
Molecular Weight	138.17 g/mol
Synonyms	Spiro[2.3]hexane-5-carbohydrazide; 5-Hydrazinylcarbonylspiro[2.3]hexane; Spiro[2.3]hexane-5-carboxylic acid hydrazide; 66036-89-3; Spirohexane carboxylic acid hydrazide; Spiro[2.3]hexanecarbohydrazide; (9CI) Spiro[2.3]hexane-5-carboxylic acid, hydrazide
EINECS	Contact for details

Quality Control

Our Spiro[2.3]Hexane-5-Carboxylic Acid, Hydrazide (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.