Description

1,2-Benzisoxazole, 5-Bromo-3-Methyl- CAS NO 66033-76-9 is a high-value brominated heterocyclic compound that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique structure makes it an essential building block for constructing complex molecules with specific electronic and steric properties. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research pipelines.
• Agrochemical Synthesis: Used in the development of new generation herbicides and fungicides, leveraging its heterocyclic core for bioactivity.
• Material Science Research: Serves as a monomer or functional unit in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and cellular processes.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and cyclization reactions to create complex fused-ring systems.
• Dye and Pigment Intermediate: Acts as a starting material for synthesizing specialized heterocyclic dyes and colorants.

Basic Information

Product Name	1,2-Benzisoxazole, 5-Bromo-3-Methyl-
CAS No.	66033-76-9
Molecular Formula	C8H6BrNO
Molecular Weight	212.05 g/mol
Synonyms	5-Bromo-3-methyl-1,2-benzisoxazole; 3-Methyl-5-bromobenzisoxazole; 5-Bromo-3-methylbenzo[d]isoxazole; 66033-76-9; 5-Bromo-3-methyl-1,2-benzoxazole; 3-Methyl-5-bromo-1,2-benzisoxazole
EINECS	Contact for details

Quality Control

Our production of 1,2-Benzisoxazole, 5-Bromo-3-Methyl- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment, supporting your R&D and scale-up activities with reliable data.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to the compound's sensitivity, it is recommended to store under an inert atmosphere for long-term preservation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.