Description

1,3-Dioxolane-4-Carboxylicacid,5-Methyl-,Methylester,trans-(9Ci) is a specialized chiral building block and protected form of a functionalized dihydroxy acid derivative. This compound matters for its role as a key intermediate in the synthesis of complex molecules, particularly in pharmaceutical and fine chemical research, where its defined stereochemistry and reactive ester group are critical. It is needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for constructing active pharmaceutical ingredients (APIs), chiral ligands, and other high-value synthetic targets.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs), particularly for antiviral, antibacterial, or neurological agents.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides where specific stereochemistry influences biological activity.
• Fine Chemical Production: Serves as a versatile building block for creating specialty chemicals, flavors, fragrances, and advanced polymers.
• Chiral Ligand and Catalyst Development: Employed as a precursor for synthesizing novel chiral auxiliaries, ligands, and organocatalysts used in asymmetric synthesis.
• Academic and Industrial Research: A valuable reagent for methodological studies in organic synthesis, exploring new reaction pathways and protecting group strategies.
• Material Science: Potential monomer or cross-linking agent in the development of specialized polymers with unique properties.

Basic Information

Product Name	1,3-Dioxolane-4-Carboxylicacid,5-Methyl-,Methylester,trans-(9Ci)
CAS No.	66003-31-4
Molecular Formula	C7H10O5
Molecular Weight	174.15 g/mol
Synonyms	trans-Methyl 5-methyl-1,3-dioxolane-4-carboxylate; (4R,5R)-(-)-4-Carbomethoxy-2,2-dimethyl-1,3-dioxolane; Methyl (4R,5R)-5-methyl-1,3-dioxolane-4-carboxylate; (4R,5R)-Methyl 5-methyl-1,3-dioxolane-4-carboxylate; trans-5-Methyl-1,3-dioxolane-4-carboxylic acid methyl ester; (R,R)-Pantolactone methyl ester derivative; Acetonide-protected glyceric acid methyl ester derivative
EINECS	Contact for details

Quality Control

Our 1,3-Dioxolane-4-Carboxylicacid,5-Methyl-,Methylester,trans-(9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and enantiomeric excess meet the high standards required for synthetic applications. Certificates of Analysis (COA) detailing specific results for assay, chiral purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.