Description

2-Bromo-4-Methyl-Nicotinic Acid Ethyl Ester is a high-purity, versatile nicotinic acid derivative serving as a critical building block in advanced organic synthesis. Its value lies in providing a functionalized pyridine core, enabling the construction of complex molecules for pharmaceutical and agrochemical research. This compound is essential for R&D chemists and process development scientists in the fine chemical, pharmaceutical intermediate, and agrochemical sectors.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and other small-molecule drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents and herbicides, leveraging its halogenated pyridine structure.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalytic systems.
• Material Science Research: Employed in the synthesis of functional organic materials and metal-organic frameworks (MOFs) due to its ester and halogen functionalities.
• Chemical Biology Probes: Utilized as a building block for synthesizing molecular probes and labeled compounds for biochemical research.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical manufacturing.

Basic Information

Product Name	2-Bromo-4-Methyl-Nicotinic Acid Ethyl Ester
CAS No.	65996-17-0
Molecular Formula	C9H10BrNO2
Molecular Weight	244.09 g/mol
Synonyms	Ethyl 2-Bromo-4-methylnicotinate; 2-Bromo-4-methylpyridine-3-carboxylic acid ethyl ester; 3-Carbethoxy-2-bromo-4-methylpyridine; 2-Bromo-4-methyl-3-pyridinecarboxylic acid ethyl ester; Ethyl 2-bromo-4-methyl-3-pyridinecarboxylate; 65996-17-0; 2-Bromo-4-methylnicotinic acid ethyl ester
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Methyl-Nicotinic Acid Ethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.