Description

2-Bromo-5-Methyl-3-(Trifluoromethyl)Pyridine is a versatile and highly functionalized pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both bromine and trifluoromethyl substituents, makes it an indispensable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Precursor: Employed in the synthesis of functionalized ligands for catalysis and in the creation of specialty polymers or liquid crystals.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Negishi) to form new carbon-carbon bonds.

Basic Information

Product Name	2-Bromo-5-Methyl-3-(Trifluoromethyl)Pyridine
CAS No.	65996-08-9
Molecular Formula	C7H5BrF3N
Molecular Weight	240.02 g/mol
Synonyms	3-(Trifluoromethyl)-2-bromo-5-methylpyridine; 2-Bromo-5-methyl-3-trifluoromethylpyridine; 5-Methyl-2-bromo-3-(trifluoromethyl)pyridine; Pyridine, 2-bromo-5-methyl-3-(trifluoromethyl)-; 2-Bromo-3-trifluoromethyl-5-methylpyridine
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Methyl-3-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee consistent quality and traceability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.