Description

2-Bromo-4-Methyl-Nicotinic Acid CAS NO 65996-07-8 is a high-purity brominated nicotinic acid derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a functionalized pyridine core that enables the construction of complex molecules with precise structural control. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug research.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides that require a functionalized pyridine moiety.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials and metal-organic frameworks (MOFs) due to its ability to introduce both halogen and carboxylic acid functionalities.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-Bromo-4-Methyl-Nicotinic Acid
CAS No.	65996-07-8
Molecular Formula	C7H6BrNO2
Molecular Weight	216.03 g/mol
Synonyms	2-Bromo-4-methylpyridine-3-carboxylic acid; 3-Carboxy-2-bromo-4-methylpyridine; 4-Methyl-2-bromonicotinic acid; 2-Bromo-4-methylnicotinic acid; 2-Bromo-4-picolinic acid (ambiguous); Nicotinic acid, 2-bromo-4-methyl-; Pyridine-3-carboxylic acid, 2-bromo-4-methyl-
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Methyl-Nicotinic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in its original packaging to minimize exposure to moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.