Description

Methyl 4,6-Dichloronicotinate is a high-purity, versatile chloronicotinate ester serving as a critical synthetic intermediate. Its value lies in providing a functionalized pyridine scaffold for constructing complex molecules in advanced research and development. This compound is essential for pharmaceutical chemists and agrochemical researchers developing new active ingredients, particularly in the synthesis of novel heterocyclic compounds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for drugs targeting the central nervous system or with nicotinic receptor activity.
• Agrochemical Synthesis: Used in the research and production of modern pesticides, herbicides, and fungicides, leveraging the bioactivity of the chlorinated pyridine core.
• Chemical Research & Development: A versatile reagent for constructing complex heterocyclic systems in medicinal chemistry and material science projects.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in catalysis and coordination chemistry.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals and performance materials requiring specific chloropyridine motifs.

Basic Information

Product Name	Methyl 4,6-Dichloronicotinate
CAS No.	65973-52-6
Molecular Formula	C7H5Cl2NO2
Molecular Weight	206.03 g/mol
Synonyms	4,6-Dichloropyridine-3-carboxylic acid methyl ester; Methyl 4,6-dichloropyridine-3-carboxylate; 3-Pyridinecarboxylic acid, 4,6-dichloro-, methyl ester; 4,6-Dichloronicotinic acid methyl ester; Methyl 4,6-dichloronicotinate; 65973-52-6
EINECS	Contact for details

Quality Control

Our Methyl 4,6-Dichloronicotinate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets exacting standards for research and industrial use. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.