Description

L-Alanine, 3-Iodo-n-[(Phenylmethoxy)Carbonyl]-, Phenylmethyl Ester is a specialized, non-natural amino acid derivative featuring an iodine substituent and a protected carboxyl group. This compound serves as a critical building block in advanced organic synthesis, particularly for the development of novel peptides and bioactive molecules. It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, proteomics research, and the development of targeted therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of iodinated peptide analogs and potential drug candidates.
• Medicinal Chemistry Research: Used to introduce iodine atoms into peptide backbones for structure-activity relationship (SAR) studies and bio-conjugation.
• Proteomics & Biochemical Tool Development: Employed in creating affinity probes, enzyme inhibitors, or labeled peptides for biochemical assays.
• Organic Synthesis Building Block: Serves as a versatile chiral synthon for constructing complex, functionalized organic molecules.
• Radiopharmaceutical Precursor: Potential use as a precursor for compounds where the iodine-127 can be exchanged for radioactive isotopes like iodine-125 or iodine-131 for imaging or therapy.
• Academic & Industrial R&D: Fundamental research tool in universities and corporate R&D labs exploring new chemical entities and bioconjugation techniques.

Basic Information

Product Name	L-Alanine, 3-Iodo-n-[(Phenylmethoxy)Carbonyl]-, Phenylmethyl Ester
CAS No.	65926-39-8
Molecular Formula	C18H18INO4
Molecular Weight	439.25 g/mol
Synonyms	N-[(Benzyloxy)carbonyl]-3-iodo-L-alanine benzyl ester; Z-3-Iodo-L-alanine benzyl ester; (S)-2-((Benzyloxy)carbonylamino)-3-iodopropanoic acid benzyl ester; 3-Iodo-N-carbobenzoxy-L-alanine benzyl ester; Cbz-3-Iodo-L-Ala-OBzl; N-Cbz-3-iodo-L-alanine benzyl ester; Benzyl (S)-2-(((benzyloxy)carbonyl)amino)-3-iodopropanoate
EINECS	Contact for details

Quality Control

Our L-Alanine, 3-Iodo-n-[(Phenylmethoxy)Carbonyl]-, Phenylmethyl Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture uptake, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee (L-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.