Description

4-Hydroxy Mestranol is a key synthetic estrogenic steroid and a primary metabolite of the progestin mestranol. This compound is of significant importance as a high-purity reference standard and a critical intermediate in the research and development of steroidal pharmaceuticals. It is essential for pharmaceutical manufacturers, analytical laboratories, and research institutions focused on endocrinology, hormone therapy, and the synthesis of novel therapeutic agents.

Application

• Pharmaceutical intermediate for the synthesis of advanced steroidal drugs and hormone therapies.
• High-purity certified reference material (CRM) for analytical method development and validation in quality control laboratories.
• Active Pharmaceutical Ingredient (API) research for novel endocrine and reproductive health treatments.
• Biochemical research tool for studying estrogen receptor activity and metabolic pathways.
• Calibration standard for chromatographic analysis (HPLC, GC) and mass spectrometry in regulatory testing.

Basic Information

Product Name	4-Hydroxy Mestranol
CAS No.	65694-22-6
Molecular Formula	C₂₁H₂₈O₃
Molecular Weight	328.45 g/mol
Synonyms	4-Hydroxymestranol; 17α-Ethynyl-3-methoxy-19-nor-17α-pregna-1,3,5(10)-trien-20-yn-4-ol; 4-Hydroxy-17α-ethynyl-3-methoxyestra-1,3,5(10)-trien-17β-ol; 3-Methoxy-17α-ethynyl-19-nor-1,3,5(10)-pregnatrien-20-yn-4-ol; 4-OH Mestranol; Mestranol, 4-hydroxy-; 4-Hydroxy-17α-ethynyl-3-methoxy-19-norpregna-1,3,5(10)-trien-20-yn-17β-ol
EINECS	Contact for details

Quality Control

Our 4-Hydroxy Mestranol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via advanced techniques like HPLC and GC-MS, to ensure it meets the stringent requirements for pharmaceutical intermediates and reference standards. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.