Description

α-(4-Bromophenyl)-α-[2-(Dimethylamino)Ethyl]Pyridine-2-Acetonitrile is a high-purity, advanced pharmaceutical intermediate with a complex molecular architecture designed for sophisticated synthesis. This compound is critical for research and development in medicinal chemistry, particularly in the construction of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers focused on developing new therapeutic agents, especially within the central nervous system (CNS) and oncology domains.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of potential drug candidates, particularly those targeting neurological receptors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead compounds.
• Active Pharmaceutical Ingredient (API) Development: Serves as a precursor in the synthesis of complex APIs for preclinical and clinical studies.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP guidelines.
• Academic Research: Employed in university and institutional labs for exploratory research in organic synthesis and pharmacology.
• Reference Standard: High-purity grades can be used as analytical reference standards for quality control and method development.

Basic Information

Product Name	α-(4-Bromophenyl)-α-[2-(Dimethylamino)Ethyl]Pyridine-2-Acetonitrile
CAS No.	65676-22-4
Molecular Formula	C17H18BrN3
Molecular Weight	344.25 g/mol
Synonyms	2-[(4-Bromophenyl)(2-(dimethylamino)ethyl)amino]-2-pyridin-2-ylacetonitrile; 2-[(4-Bromophenyl)[2-(dimethylamino)ethyl]amino]-2-(pyridin-2-yl)acetonitrile; α-(4-Bromophenyl)-α-[2-(dimethylamino)ethyl]-2-pyridineacetonitrile; 2-Pyridineacetonitrile, α-(4-bromophenyl)-α-[2-(dimethylamino)ethyl]-; (4-Bromophenyl)2-(dimethylamino)ethylacetonitrile; 65676-22-4; PharmIntermediate 65676-22-4
EINECS	Contact for details

Quality Control

Our α-(4-Bromophenyl)-α-[2-(Dimethylamino)Ethyl]Pyridine-2-Acetonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) with full traceability are provided for each lot. We support development under quality agreements and can supply material suitable for use in cGMP environments upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.