Description

α-(4-Chlorophenyl)-α-[2-(Dimethylamino)Ethyl]Pyridine-2-Acetonitrile CAS NO 65676-21-3 is a high-value, nitrogen-containing heterocyclic compound featuring a pyridine core with chlorophenyl and dimethylaminoethyl substituents. This complex molecular structure makes it a critical advanced pharmaceutical intermediate (API) and a versatile building block for organic synthesis. It is primarily required by pharmaceutical R&D and fine chemical manufacturing sectors for developing novel active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug molecules, particularly those targeting neurological and cardiovascular pathways.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging its chlorophenyl and pyridine motifs.
• Ligand and Catalyst Development: Acts as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Organic Electronic Materials: Investigated as a building block for charge-transport materials in OLEDs and other electronic applications due to its conjugated system.
• Academic and Industrial Research: Employed in chemical research for studying structure-activity relationships (SAR) and developing new synthetic methodologies.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target compounds.

Basic Information

Product Name	α-(4-Chlorophenyl)-α-[2-(Dimethylamino)Ethyl]Pyridine-2-Acetonitrile
CAS No.	65676-21-3
Molecular Formula	C₁₇H₁₈ClN₃
Molecular Weight	299.80 g/mol
Synonyms	2-[(4-Chlorophenyl)[2-(dimethylamino)ethyl]amino]pyridine-3-carbonitrile; 2-Pyridineacetonitrile, α-(4-chlorophenyl)-α-[2-(dimethylamino)ethyl]-; α-(4-Chlorophenyl)-α-[2-(dimethylamino)ethyl]-2-pyridineacetonitrile; 65676-21-3; 4-Chloro-α-(2-(dimethylamino)ethyl)α-phenyl-2-pyridineacetonitrile
EINECS	Contact for details

Quality Control

Our α-(4-Chlorophenyl)-α-[2-(Dimethylamino)Ethyl]Pyridine-2-Acetonitrile is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.