Description

.Alpha.-L-Idopyranuronic Acid, 5-C-(Acetyloxy)-, Methyl Ester, Tetraacetate is a high-purity, fully acetylated derivative of iduronic acid, a key monosaccharide component of glycosaminoglycans. This compound is a critical advanced intermediate for the synthesis of complex carbohydrates, heparan sulfate analogs, and other bioactive glycoconjugates. It is essential for researchers and manufacturers in the pharmaceutical and biochemical sectors developing novel therapeutics and diagnostic tools.

Application

• Pharmaceutical Intermediate: Key building block for the chemical and enzymatic synthesis of heparin/heparan sulfate mimetics and oligosaccharides with anticoagulant or anti-inflammatory properties.
• Glycobiology Research: Used as a standard or precursor in studies of carbohydrate-protein interactions, enzyme substrate specificity, and metabolic pathways involving iduronic acid.
• Bioconjugate Development: Serves as a starting material for creating labeled probes, glycan arrays, or drug conjugates for targeted delivery and diagnostic applications.
• Chemical Synthesis: A protected monosaccharide donor in oligosaccharide assembly, leveraging its acetyl groups for selective deprotection strategies.

Basic Information

Product Name	.Alpha.-L-Idopyranuronic Acid, 5-C-(Acetyloxy)-, Methyl Ester, Tetraacetate
CAS No.	65615-68-1
Molecular Formula	C19H24O14
Molecular Weight	476.39 g/mol
Synonyms	Methyl (2S,3S,4S,5R,6S)-3,4,5-Triacetoxy-6-((S)-1-acetoxy-2-methoxy-2-oxoethoxy)oxane-2-carboxylate; Methyl 2,3,4-tri-O-acetyl-α-L-idopyranosiduronic acid 1,5-lactone 5-acetate; 1,5-Lactone of methyl (2,3,4-tri-O-acetyl-α-L-idopyranosyluronate) 5-acetate; α-L-Idopyranuronic acid, methyl ester, 2,3,4,5-tetraacetate; L-Iduronic acid derivative, fully acetylated methyl ester
EINECS	Contact for details

Quality Control

Our .Alpha.-L-Idopyranuronic Acid derivative is produced under controlled conditions to ensure batch-to-batch consistency and high chemical purity. Each lot undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to meet the exacting standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after each use to maintain stability and prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.