Description

Ethyl 2-Amino-4-Trifluoromethylbenzoate is a high-purity, versatile benzoate ester derivative characterized by its amino and trifluoromethyl functional groups. This compound is a critical pharmaceutical intermediate and building block in advanced organic synthesis, valued for its role in modulating the biological activity and physicochemical properties of target molecules. It is primarily utilized by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Serves as a building block for developing novel herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances lipophilicity and biological activity.
• Liquid Crystal & OLED Material Research: Used in the development of advanced electronic materials and organic light-emitting diodes (OLEDs) due to its molecular structure and electronic properties.
• Dye & Pigment Manufacturing: Acts as an intermediate in the production of specialized dyes and pigments, contributing to color fastness and stability.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, amide bond formation, and other transformations to introduce the 2-amino-4-trifluoromethylbenzoate moiety into complex molecules.
• Chemical Research & Development: Essential for academic and industrial R&D projects focused on fluorinated compounds and their unique chemical behaviors.

Basic Information

Product Name	Ethyl 2-Amino-4-Trifluoromethylbenzoate
CAS No.	65568-55-0
Molecular Formula	C10H10F3NO2
Molecular Weight	233.19 g/mol
Synonyms	Ethyl 2-Amino-α,α,α-trifluoro-p-toluate; Benzoic acid, 2-amino-4-(trifluoromethyl)-, ethyl ester; 2-Amino-4-trifluoromethylbenzoic acid ethyl ester; Ethyl 2-amino-4-(trifluoromethyl)benzoate; 4-(Trifluoromethyl)anthranilic acid ethyl ester; Ethyl 4-(trifluoromethyl)anthranilate; 2-Amino-α,α,α-trifluoro-p-toluic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 2-Amino-4-Trifluoromethylbenzoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure it meets the high-purity standards required for pharmaceutical and advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.