Description

2-Bromo-3-Chloro-5-Picoline is a halogenated pyridine derivative, a versatile and high-value building block in advanced organic synthesis. Its precise molecular structure makes it a critical intermediate for the development of complex active pharmaceutical ingredients (APIs) and specialty agrochemicals. This compound is essential for research and production in the pharmaceutical, agrochemical, and material science industries, where it serves as a key precursor for creating novel molecules with targeted properties.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of complex drug candidates, particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides, where its halogenated picoline structure contributes to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the synthesis of functionalized organic materials, including liquid crystals and organic semiconductors.
• Chemical Research & Development: A valuable reagent for medicinal chemistry and process chemistry R&D, enabling structure-activity relationship (SAR) studies.
• Custom Synthesis: Used by contract research and manufacturing organizations (CROs/CMOs) for the custom synthesis of client-specific target molecules.

Basic Information

Item	Detail
Product Name	2-Bromo-3-Chloro-5-Picoline
CAS No.	65550-81-4
Molecular Formula	C6H5BrClN
Molecular Weight	206.47 g/mol
Synonyms	2-Bromo-3-chloro-5-methylpyridine; 3-Chloro-2-bromo-5-methylpyridine; 5-Methyl-2-bromo-3-chloropyridine; 2-Bromo-3-chloro-5-picoline; 3-Chloro-2-bromo-5-picoline; 2-Bromo-3-chloro-5-methylpyridine; 5-Picoline, 2-bromo-3-chloro-
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-3-Chloro-5-Picoline is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure consistency and purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment ensures the material meets the stringent requirements for use in pharmaceutical and agrochemical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Melting Point	Contact for details
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.