Description

2-Bromo-5-Iodonicotinic Acid is a halogenated nicotinic acid derivative that serves as a versatile and high-value synthetic intermediate. Its molecular structure, featuring both bromine and iodine substituents, makes it a critical building block for constructing complex heterocyclic systems and functionalized pyridine scaffolds. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug molecules, particularly those targeting neurological disorders and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with specific modes of action.
• Ligand Synthesis: Building block for creating specialized ligands used in catalysis and material science.
• Chemical Biology Probes: Employed in the design of molecular probes for studying enzyme function and biological pathways.
• Organic Electronics: Intermediate for synthesizing functionalized pyridine-based compounds used in organic light-emitting diodes (OLEDs) and semiconductors.
• Cross-Coupling Reactions: Serves as a substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.

Basic Information

Product Name	2-Bromo-5-Iodonicotinic Acid
CAS No.	65550-80-3
Molecular Formula	C6H3BrINO2
Molecular Weight	327.90 g/mol
Synonyms	5-Iodo-2-bromonicotinic acid; 2-Bromo-5-iodopyridine-3-carboxylic acid; 3-Carboxy-2-bromo-5-iodopyridine; Nicotinic acid, 2-bromo-5-iodo-; 65550-80-3; 2-Bromo-5-iodo-3-pyridinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Iodonicotinic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the stringent requirements of research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. The product is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.