Description

3-Pyridinecarbonyl Chloride, 6-Chloro-2-Methoxy- is a versatile and highly reactive heterocyclic building block, primarily used as an acylating agent in organic synthesis. Its core value lies in enabling the efficient introduction of the 6-chloro-2-methoxynicotinoyl moiety, a key structural motif in advanced chemical development. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it serves as a critical intermediate in the creation of active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system, inflammation, and metabolic disorders.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for biological activity.
• Ligand and Catalyst Development: Serves as a building block for creating complex ligands used in catalysis and material science.
• Custom Synthesis and R&D: Employed in research laboratories for the construction of complex pyridine derivatives and for probing new chemical spaces in medicinal chemistry.
• Peptide Mimetics: Useful in the design and synthesis of peptide analogs and enzyme inhibitors where the nicotinoyl group is a required pharmacophore.

Basic Information

Product Name	3-Pyridinecarbonyl Chloride, 6-Chloro-2-Methoxy-
CAS No.	65515-30-2
Molecular Formula	C7H5Cl2NO2
Molecular Weight	206.03 g/mol
Synonyms	6-Chloro-2-methoxynicotinoyl chloride; 2-Methoxy-6-chloronicotinoyl chloride; 6-Chloro-2-methoxypyridine-3-carbonyl chloride; 3-Carbonyl chloride-6-chloro-2-methoxypyridine; 6-Chloro-2-methoxy-3-pyridinecarboxylic acid chloride
EINECS	Contact for details

Quality Control

Our 3-Pyridinecarbonyl Chloride, 6-Chloro-2-Methoxy- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee supply reliability and quality assurance for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid/organic solvent derivative, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.