Description

H-D-Asp-Ome CAS NO 65414-78-0 is a protected aspartic acid derivative, specifically the methyl ester of N-Boc-D-aspartic acid β-tert-butyl ester. This compound is a crucial chiral building block in organic synthesis, prized for its role in introducing the D-aspartic acid moiety with orthogonal protecting groups. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors who require high-purity intermediates for the synthesis of peptides, peptidomimetics, and complex bioactive molecules.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the production of active pharmaceutical ingredients (APIs) and investigational new drugs.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate D-aspartic acid residues.
• Proteomics Research: Serves as a standard or building block in biochemical research involving amino acid analysis and protein studies.
• Asymmetric Synthesis: Employed in the preparation of non-natural amino acids and complex organic molecules requiring stereochemical control.
• Bioconjugation: Useful in the development of linker molecules and modified biomolecules for diagnostic and therapeutic applications.

Basic Information

Product Name	H-D-Asp-Ome
CAS No.	65414-78-0
Molecular Formula	C14H25NO6
Molecular Weight	303.35 g/mol
Synonyms	N-Boc-D-aspartic acid β-tert-butyl ester methyl ester; (R)-2-((tert-Butoxycarbonyl)amino)butanedioic acid 4-tert-butyl 1-methyl ester; Boc-D-Asp(OtBu)-OMe; Methyl N-(tert-butoxycarbonyl)-D-aspartate 4-tert-butyl ester; Boc-D-Aspartic acid β-tert-butyl ester methyl ester; D-Aspartic acid, N-Boc-β-tert-butyl methyl ester; (R)-Methyl 2-((tert-butoxycarbonyl)amino)-4-((tert-butoxy)oxy)-4-oxobutanoate
EINECS	Contact for details

Quality Control

Our H-D-Asp-Ome is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure compliance with high-grade standards suitable for research and cGMP manufacturing. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and specific impurities is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider using a desiccant.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.