Description

4-Chloro-2-Nitropyridine is a versatile halogenated nitropyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both an electron-withdrawing nitro group and a reactive chloro substituent, makes it an indispensable intermediate for constructing complex heterocyclic systems. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting neurological disorders and infectious diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the pyridine core provides essential bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the development of organic electronic materials, such as charge-transport layers and light-emitting components.
• Dye and Pigment Manufacturing: Acts as an intermediate for synthesizing complex azo dyes and other colorants with specific light-fastness properties.
• Custom Synthesis and Contract Manufacturing: A fundamental reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving diverse R&D projects.

Basic Information

Item	Details
Product Name	4-Chloro-2-Nitropyridine
CAS No.	65370-42-5
Molecular Formula	C5H3ClN2O2
Molecular Weight	158.54 g/mol
Synonyms	2-Nitro-4-chloropyridine; 4-Chloro-2-nitropyridine; 4-Chloro-2-nitro-pyridine; 2-Nitro-4-chloro-pyridine; Pyridine, 4-chloro-2-nitro-; 4-Chloro-2-nitro-pyridin; 4-Chloro-2-nitro-pyridine (ACD/Name 4.0)
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-Nitropyridine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant secondary packaging.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	68°C - 72°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.