Description

Cyclobutanecarboxylic Acid, 1-Methyl-, Ethyl Ester CAS NO 65338-28-5 is a specialized organic ester compound featuring a cyclobutane ring, valued for its unique steric and electronic properties as a building block in advanced chemical synthesis. This compound matters as a key chiral intermediate and precursor for developing complex molecules in high-value research and manufacturing sectors. It is primarily needed by pharmaceutical R&D laboratories, agrochemical innovators, and specialty chemical manufacturers seeking to create novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a crucial chiral building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used as a precursor in the research and development of new-generation herbicides and fungicides, leveraging the constrained cyclobutane structure.
• Ligand and Catalyst Development: Employed in organometallic chemistry for the creation of specialized ligands and catalysts used in asymmetric synthesis.
• Fragrance and Flavor Chemistry: Acts as an intermediate for synthesizing unique musk and woody aroma chemicals due to its specific ring structure.
• Material Science Research: Investigated as a monomer or cross-linking agent for producing polymers with tailored thermal and mechanical properties.
• Organic Synthesis Reagent: Utilized in academic and industrial research for cycloaddition reactions and the construction of complex, strained ring systems.

Basic Information

Item	Detail
Product Name	Cyclobutanecarboxylic Acid, 1-Methyl-, Ethyl Ester
CAS No.	65338-28-5
Molecular Formula	C8H14O2
Molecular Weight	142.20 g/mol
Synonyms	Ethyl 1-Methylcyclobutanecarboxylate; 1-Methylcyclobutanecarboxylic Acid Ethyl Ester; Ethyl 1-Methylcyclobutanecarboxylate; NSC 406916; 1-Methylcyclobutane-1-carboxylic acid ethyl ester; Ethyl 1-methyl-1-cyclobutanecarboxylate
EINECS	Contact for details

Quality Control

Our Cyclobutanecarboxylic Acid, 1-Methyl-, Ethyl Ester is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing all critical specifications. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Purity (HPLC)	≥ 96.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.