Description

(17R)-3-(Dimethylsulfamoyloxy)-13-Ethyl-18,19-Dinorpregna-1,3,5(10)-Trien-20-Yn-17-Ol is a high-purity synthetic steroid derivative, also known by its CAS number 65323-80-0. This compound is a critical pharmaceutical intermediate valued for its specific stereochemistry and functional groups, which are essential for advanced drug synthesis. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents.

Application

This specialized steroid derivative serves as a key building block in advanced organic synthesis. Its primary applications include:

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel steroidal drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard or a starting material in metabolic pathway studies and receptor binding assays.
• Hormone Analog Development: Serves as a core structure for developing new analogs with potential therapeutic activity.
• Process Chemistry: Employed in scale-up and optimization studies for the commercial production of complex molecules.
• Academic Research: Utilized in university and institutional labs for methodological development in synthetic organic chemistry.

Basic Information

Product Name	(17R)-3-(Dimethylsulfamoyloxy)-13-Ethyl-18,19-Dinorpregna-1,3,5(10)-Trien-20-Yn-17-Ol
CAS No.	65323-80-0
Molecular Formula	C25H35NO4S
Molecular Weight	445.62 g/mol
Synonyms	13-Ethyl-17-hydroxy-18,19-dinor-17α-pregna-1,3,5(10)-trien-20-yn-3-yl dimethylsulfamate; (17R)-3-[(Dimethylamino)sulfonyl]oxy-13-ethyl-18,19-dinorpregna-1,3,5(10)-trien-20-yn-17-ol; 17α-Ethynyl-13β-ethyl-17β-hydroxy-18,19-dinorandrosta-1,3,5(10)-trien-3-yl dimethylsulfamate; Steroid Derivative 65323-80-0; Dimethylsulfamoyloxy Pregnenyne Derivative
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide material that meets high-purity specifications suitable for research and pharmaceutical development. Certificates of Analysis (COA) are available upon request, detailing parameters such as purity, identity, and impurity profiles. Quality is managed in line with cGMP principles where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.