Description

2-(4-Azidophenyl)-2-Oxo-Acetaldehyde is a specialized aromatic aldehyde derivative featuring a reactive azido functional group. This compound is valued for its role as a versatile photoaffinity labeling agent and a key synthetic intermediate in advanced organic synthesis. It is primarily utilized by researchers and manufacturers in the pharmaceutical, bioconjugation, and materials science sectors for developing novel probes, polymers, and active pharmaceutical ingredients (APIs).

Application

• Photoaffinity Labeling: Acts as a critical reagent for covalently tagging and studying biological targets, such as proteins and enzymes, upon UV light activation.
• Click Chemistry: Serves as a precursor for azide-alkyne cycloaddition (CuAAC) reactions, enabling the synthesis of complex molecular architectures.
• Polymer & Materials Science: Used in the synthesis of functional polymers, dendrimers, and smart materials where the azide group facilitates cross-linking or post-polymerization modification.
• Pharmaceutical Intermediate: Employed in the research and development of new drug candidates, particularly in constructing heterocyclic cores and bioconjugates.
• Surface Functionalization: Applied to modify surfaces (e.g., chips, nanoparticles) with azido groups for subsequent biomolecule immobilization.
• Proteomics Research: Utilized in chemical proteomics to identify and characterize small molecule-protein interactions within complex biological systems.

Basic Information

Product Name	2-(4-Azidophenyl)-2-Oxo-Acetaldehyde
CAS No.	65322-07-8
Molecular Formula	C8H5N3O2
Molecular Weight	175.15 g/mol
Synonyms	4-Azidobenzoylformaldehyde; p-Azidophenylglyoxal; 2-Oxo-2-(4-azidophenyl)acetaldehyde; (4-Azidophenyl)(oxo)acetaldehyde; Glyoxal, (p-azidophenyl)-; Azidobenzoylformaldehyde
EINECS	Contact for details

Quality Control

Our 2-(4-Azidophenyl)-2-Oxo-Acetaldehyde is produced under stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and synthesis. A Certificate of Analysis (COA) detailing specific batch results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation and degradation. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.