Description

1,1-(4-Fluorophenyl)-(Pyridin-4-Yl)Methanol is a high-value fluorinated pyridine derivative, serving as a critical chiral building block and synthetic intermediate in advanced organic chemistry. Its unique structure, combining a fluorinated phenyl ring with a pyridyl methanol group, makes it indispensable for constructing complex molecules with tailored biological and physical properties. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and synthesis of potential drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Research: Used as a precursor in developing new-generation pesticides and herbicides, leveraging the fluorine atom for enhanced bioactivity and environmental stability.
• Ligand Synthesis: Serves as a starting material for creating sophisticated chiral ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Investigated for incorporation into advanced polymers and liquid crystals to modify electronic properties and thermal stability.
• Academic & Process Chemistry: Employed in methodological studies and scale-up process development for fine chemical manufacturing.

Basic Information

Product Name	1,1-(4-Fluorophenyl)-(Pyridin-4-Yl)Methanol
CAS No.	65214-62-2
Molecular Formula	C₁₂H₁₀FNO
Molecular Weight	203.21 g/mol
Synonyms	(4-Fluorophenyl)(pyridin-4-yl)methanol; 4-Pyridinemethanol, α-(4-fluorophenyl)-; α-(4-Fluorophenyl)-4-pyridinemethanol; 1-(4-Fluorophenyl)-1-(4-pyridyl)methanol; (4-Fluorobenzene)(4-pyridine)methanol; 65214-62-2; (4-Fluorophenyl)(4-pyridinyl)methanol
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our fine chemical intermediates. Each batch of 1,1-(4-Fluorophenyl)-(Pyridin-4-Yl)Methanol is produced and analyzed under current Good Manufacturing Practice (cGMP) principles for non-API starting materials. Identity, purity, and impurity profiles are verified using advanced analytical techniques including HPLC, GC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to ensure full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.