Description

Methyl 10-[(Hydroxyamino)Carbonyl]-1,4-Dioxa-7-Azaspiro[4.5]Decane-7-Carboxylate is a specialized heterocyclic building block featuring a spirocyclic and hydroxamic acid derivative structure. This compound is valued for its unique molecular architecture, which makes it a versatile intermediate in advanced organic synthesis and medicinal chemistry research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecules with potential biological activity.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in protease inhibitor and metalloenzyme modulator research.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to explore new therapeutic candidates.
• Agrochemical Synthesis: Serves as a precursor in the design and synthesis of new generation herbicides and fungicides with novel modes of action.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying enzyme function and cellular pathways due to its hydroxamic acid group.
• Complex Ligand Synthesis: Acts as a sophisticated ligand precursor in coordination chemistry and catalyst design.
• Advanced Material Development: Investigated as a monomer or cross-linking agent for specialty polymers with specific thermal or chemical resistance properties.

Basic Information

Product Name	Methyl 10-[(Hydroxyamino)Carbonyl]-1,4-Dioxa-7-Azaspiro[4.5]Decane-7-Carboxylate
CAS No.	65202-61-1
Molecular Formula	C11H18N2O6
Molecular Weight	274.27 g/mol
Synonyms	Methyl 10-(hydroxycarbamoyl)-1,4-dioxa-7-azaspiro[4.5]decane-7-carboxylate; 7-Carbomethoxy-1,4-dioxa-7-azaspiro[4.5]decane-10-hydroxamic acid; 1,4-Dioxa-7-azaspiro[4.5]decane-7-carboxylic acid, 10-[(hydroxyamino)carbonyl]-, methyl ester; Spirocyclic hydroxamate ester; Methyl N-hydroxy-1,4-dioxa-7-azaspiro[4.5]decane-7,10-dicarboximide
EINECS	Contact for details

Quality Control

Our Methyl 10-[(Hydroxyamino)Carbonyl]-1,4-Dioxa-7-Azaspiro[4.5]Decane-7-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.