Description

(3R,3Aβ)-4,5,6,6Aβ,9A,9Bβ-Hexahydro-6α,9Aα-Dimethylspiro[Azuleno[4,5-B]Furan-3(2H),2'-Oxirane]-2,9(3Ah)-Dione is a high-purity, complex spirocyclic compound featuring a fused azulene-furan-oxirane structure. This compound is valued as a critical chiral intermediate and building block in advanced organic synthesis, enabling the construction of novel molecular architectures. It is primarily sought after by pharmaceutical R&D and fine chemical sectors for the development of new active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly for complex small-molecule drugs.
• Advanced Organic Synthesis: Serves as a sophisticated building block for constructing complex natural product analogs and spirocyclic compounds.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and library synthesis to explore new chemical spaces.
• Asymmetric Catalysis Substrate: Employed in the development and testing of new chiral catalysts and synthetic methodologies.
• Fine Chemical Production: Utilized in the multi-step synthesis of high-value specialty chemicals and performance materials.
• Academic & Industrial R&D: A valuable compound for fundamental research in organic chemistry and material science.

Basic Information

Product Name	(3R,3Aβ)-4,5,6,6Aβ,9A,9Bβ-Hexahydro-6α,9Aα-Dimethylspiro[Azuleno[4,5-B]Furan-3(2H),2'-Oxirane]-2,9(3Ah)-Dione
CAS No.	65179-88-6
Molecular Formula	C₁₆H₁₈O₄
Molecular Weight	274.31 g/mol
Synonyms	6α,9aα-Dimethylspiro[azuleno[4,5-b]furan-3(2H),2'-oxirane]-2,9(3aH)-dione, 4,5,6,6aβ,9a,9bβ-hexahydro-, (3R,3aβ)-; Spiro[azuleno[4,5-b]furan-3(2H),2'-oxirane]-2,9(3aH)-dione, 4,5,6,6aβ,9a,9bβ-hexahydro-6α,9aα-dimethyl-, (3R,3aβ)-; CAS 65179-88-6; Azuleno-furan-oxirane spiro compound
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch undergoes comprehensive analytical characterization, including chiral purity verification, to ensure reproducible high quality and structural integrity for demanding synthetic applications. A detailed Certificate of Analysis (COA) providing identity, purity (HPLC/Chiral HPLC), and impurity profile is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.