Description

6-Chloro-5-Methylpyridine-3-Carboxamide is a high-purity, versatile pyridine derivative serving as a critical building block in advanced organic synthesis. This compound is essential for research and development chemists seeking to introduce specific functionalized pyridine motifs into complex molecular architectures. Its primary value lies in enabling the synthesis of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals, making it indispensable for the pharmaceutical, agrochemical, and material science industries.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides due to its bioactive pyridine core.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or light-emitting components.
• Chemical Biology Probes: Utilized as a scaffold for designing molecular probes to study biological pathways and enzyme functions.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up production under cGMP conditions.

Basic Information

Item	Detail
Product Name	6-Chloro-5-Methylpyridine-3-Carboxamide
CAS No.	65169-44-0
Molecular Formula	C7H7ClN2O
Molecular Weight	170.60 g/mol
Synonyms	5-Methyl-6-chloronicotinamide; 3-Carbamoyl-6-chloro-5-methylpyridine; 6-Chloro-5-methyl-3-pyridinecarboxamide; 6-Chloro-5-methylnicotinamide; 6-Chloro-5-methylpyridine-3-carboxylic acid amide; 2-Chloro-5-(aminocarbonyl)-3-methylpyridine; 3-Aminocarbonyl-6-chloro-5-methylpyridine
EINECS	Contact for details

Quality Control

Every batch of 6-Chloro-5-Methylpyridine-3-Carboxamide is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.