Description

Methyl (5E)-7-(6-((1E)-3-[(Trimethylsilyl)Oxy]-1-Octenyl)-2,3-Dioxabicyclo[2.2.1]Hept-5-Yl)-5-Heptenoate is a high-purity, advanced synthetic intermediate featuring a complex bicyclic structure with strategically positioned functional groups. This compound is of significant value in organic synthesis, particularly for constructing prostaglandin analogs and other bioactive molecules due to its protected hydroxyl and ester functionalities. It is primarily sought after by research institutions and pharmaceutical development companies engaged in the synthesis of novel therapeutic agents and fine chemicals.

Application

• Key Intermediate in Prostaglandin Synthesis: Serves as a critical building block for the preparation of prostaglandin and prostacyclin analogs, which are important for pharmacological research.
• Pharmaceutical Research & Development: Used in medicinal chemistry for the discovery and development of new drug candidates targeting inflammation, cardiovascular conditions, and other physiological pathways.
• Organic Synthesis Reagent: Employed in complex multi-step syntheses to introduce specific chiral centers and functional group arrays.
• Biochemical Tool Compound: Utilized in academic and industrial labs to study enzyme interactions and biological signaling mechanisms.
• Fine Chemical Production: Acts as a precursor in the manufacture of specialized, high-value chemicals for advanced material science applications.

Basic Information

Product Name	Methyl (5E)-7-(6-((1E)-3-[(Trimethylsilyl)Oxy]-1-Octenyl)-2,3-Dioxabicyclo[2.2.1]Hept-5-Yl)-5-Heptenoate
CAS No.	65147-48-0
Molecular Formula	C22H38O5Si
Molecular Weight	410.62 g/mol
Synonyms	Methyl 7-[6-[(1E)-3-[(Trimethylsilyl)oxy]-1-octen-1-yl]-2,3-dioxabicyclo[2.2.1]hept-5-yl]-5-heptenoate; Prostaglandin Intermediate; PG Intermediate; (5E)-7-(6-((1E)-3-[(Trimethylsilyl)Oxy]-1-Octenyl)-2,3-Dioxabicyclo[2.2.1]Hept-5-Yl)-5-Heptenoic Acid Methyl Ester; TMS-protected Prostaglandin Synthon; CAS 65147-48-0
EINECS	Contact for details

Quality Control

Our Methyl (5E)-7-(6-((1E)-3-[(Trimethylsilyl)Oxy]-1-Octenyl)-2,3-Dioxabicyclo[2.2.1]Hept-5-Yl)-5-Heptenoate is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as specified on the label or COA. This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Purity (HPLC, Area %)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.