Description

(S)-Benzyl 2-Hydroxy-3-Methylbutanoate is a high-purity chiral building block and intermediate of significant value in asymmetric synthesis. This compound matters because its defined stereochemistry and functional groups make it a versatile precursor for constructing complex molecules with high enantiomeric purity. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for developing active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and cardiovascular drug research.
• Agrochemical Synthesis: Used in the production of chiral pesticides and herbicides, where stereochemistry is crucial for biological activity and environmental safety.
• Fine Chemical Production: Serves as a building block for fragrances, flavors, and other high-value specialty chemicals requiring specific optical purity.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in academic and industrial research to develop new catalytic methodologies.
• Peptide Mimetics: Utilized in the synthesis of peptidomimetics and other bioactive compounds that incorporate hydroxy acid motifs.

Basic Information

Product Name	(S)-Benzyl 2-Hydroxy-3-Methylbutanoate
CAS No.	65138-05-8
Molecular Formula	C12H16O3
Molecular Weight	208.25 g/mol
Synonyms	(S)-Benzyl 2-Hydroxy-3-methylbutyrate; (S)-Benzyl 2-Hydroxyisovalerate; (S)-2-Hydroxy-3-methylbutyric Acid Benzyl Ester; L-Benzyl 2-Hydroxy-3-methylbutanoate; Benzyl (S)-2-Hydroxy-3-methylbutanoate; (S)-Benzyl O-Isopropylglycolate; (S)-Benzyl α-Hydroxyisovalerate
EINECS	Contact for details

Quality Control

Our (S)-Benzyl 2-Hydroxy-3-Methylbutanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards, with a typical focus on chiral purity (enantiomeric excess) and chemical assay. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.